The 26.01 Data Release includes data from the following studies: Human data Arivale Scientific Wellness Study (SWS) The study provides data from over 900 participants in the Arivale-Providence Feasibility Study of Scientific Wellness, a 3-year longitudinal pilot examining the impact of personalized health interventions. Data collection included clinical and functional lab tests, genetics, gut microbiome … Data Release 26.01 | January 2026
The 25.10 Data Release includes data from the following studies: Human data The New England Centenarian Study APOE (NECS_APOE) The New England Centenarian Study APOE project (NECS_APOE) explores how the protective APOE e2 allele shapes metabolism in aging. The complete dataset includes serum metabolomics and cognitive assessments from ~200 participants—centenarians, their offspring, and controls—all free … Data Release 25.10 | October 2025
The 25.9 Data Release includes data from the following studies: Non-Human data LC Cross-Species Fibroblast Study (LC_CP_OMICS) This study applied multiomic assays (metabolomics and proteomics) to a large-scale cross species fibroblast cell culture collection derived from nearly 150 primate, bat, rodent, and bird species to determine factors related to aging and longevity.
The 25.8 Data Release includes data from the following studies: Human data The Cardiovascular Health Study (CHS) This study indexes data from the dbGaP repository. The Cardiovascular Health Study (CHS) is a prospective study of cardiovascular risk factors in adults 65+. It enrolled 5,888 participants from four U.S. communities (1989–1993) and included clinic exams, cognitive … Data Release 25.8 | August 2025
The 25.7 Data Release includes data from the following studies: Human data Human Serum Determinants of Aging This study features an investigation of human longevity using metabolomics and proteomics, data collected through a case-cohort design. Longevity cases were defined as individuals who lived longer than 98% of their peers, based on U.S. life expectancy data. … Data Release 25.7 | July 2025
The 25.6 Data Release includes data from the following studies: Human data Shotgun Metagenomics Analysis of the Gut Microbiome in ILO (ILOMGS) The study provides data from 220 samples including 78 centenarian samples (over 100 years of age) and 148 younger samples (50-99). The samples were collected as part of the Integrative longevity Omics (ILO) … Data Release 25.6 | June 2025
The 25.4 Data Release includes data from the following studies: Human data A Simulated Data Set of Extreme Longevity This study features a synthetic dataset of 19,859 participants, generated by Syntegra Inc. in 2022 using a transformer-based language model. The simulation was based on a real dataset of 4,203 individuals from the New England Centenarian … Data Release 25.4 | April 2025
Presented on April 24, 2025 The ELITE Portal Technical Workshop introduces ELITE Portal infrastructure, how to find data and metadata, and how to download and join data in preparation for downstream analyses. For slides and tutorial information, visit the ELITE Portal Technical Workshop space on Synapse.
Presented on May 16, 2025 by Dr. Michael Province, PhD Description: Pedigree OMIC data, such as from the Long Life Family Study (LLFS) are powerful for detecting genomic signals for aging traits, diseases and longevity. But unlike population data of unrelated individuals, pedigree data violate the basic statistical assumptions of almost all hypothesis tests and … Analysis of Pedigree OMIC Data Webinar
Welcome to the Exceptional Longevity Translational Resources (ELITE) Portal! The ELITE Portal (eliteportal.synapse.org) is a new research hub for disseminating data and other resources from translational longevity research projects. How do I use the ELITE Portal? Join us for our upcoming ELITE Portal Technical Workshop to learn how to navigate the portal, explore metadata, and … Welcome to the ELITE Portal!
The 25.2 Data Release includes data from the following studies: Human data The Long Life Family Study (LLFS), RNA Sequencing data The Long Life Family Study (LLFS) is an international collaborative effort investigating the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited based on clustering of exceptional survival, identified … Data Release 25.2 | February 2025
The 24.12 Data Release includes data from the following studies: Human data The Long Life Family Study (LLFS), Whole Genome Sequencing data The Long Life Family Study (LLFS) is an international collaborative effort investigating the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited based on clustering of exceptional survival, … Data Release 24.12 | December 2024