The 25.7 Data Release includes data from the following studies: Human data Human Serum Determinants of Aging This study features an investigation of human longevity using metabolomics and proteomics, data collected through a case-cohort design. Longevity cases were defined as individuals who lived longer than 98% of their peers, based on U.S. life expectancy data. … Data Release 25.7 | July 2025
The 25.6 Data Release includes data from the following studies: Human data Shotgun Metagenomics Analysis of the Gut Microbiome in ILO (ILOMGS) The study provides data from 220 samples including 78 centenarian samples (over 100 years of age) and 148 younger samples (50-99). The samples were collected as part of the Integrative longevity Omics (ILO) … Data Release 25.6 | June 2025
The 25.4 Data Release includes data from the following studies: Human data A Simulated Data Set of Extreme Longevity This study features a synthetic dataset of 19,859 participants, generated by Syntegra Inc. in 2022 using a transformer-based language model. The simulation was based on a real dataset of 4,203 individuals from the New England Centenarian … Data Release 25.4 | April 2025
Presented on April 24, 2025 The ELITE Portal Technical Workshop introduces ELITE Portal infrastructure, how to find data and metadata, and how to download and join data in preparation for downstream analyses. For slides and tutorial information, visit the ELITE Portal Technical Workshop space on Synapse.
Presented on May 16, 2025 by Dr. Michael Province, PhD Description: Pedigree OMIC data, such as from the Long Life Family Study (LLFS) are powerful for detecting genomic signals for aging traits, diseases and longevity. But unlike population data of unrelated individuals, pedigree data violate the basic statistical assumptions of almost all hypothesis tests and … Analysis of Pedigree OMIC Data Webinar
Welcome to the Exceptional Longevity Translational Resources (ELITE) Portal! The ELITE Portal (eliteportal.synapse.org) is a new research hub for disseminating data and other resources from translational longevity research projects. How do I use the ELITE Portal? Join us for our upcoming ELITE Portal Technical Workshop to learn how to navigate the portal, explore metadata, and … Welcome to the ELITE Portal!
The 25.2 Data Release includes data from the following studies: Human data The Long Life Family Study (LLFS), RNA Sequencing data The Long Life Family Study (LLFS) is an international collaborative effort investigating the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited based on clustering of exceptional survival, identified … Data Release 25.2 | February 2025
The 24.12 Data Release includes data from the following studies: Human data The Long Life Family Study (LLFS), Whole Genome Sequencing data The Long Life Family Study (LLFS) is an international collaborative effort investigating the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited based on clustering of exceptional survival, … Data Release 24.12 | December 2024
The 24.9 Data Release includes data from the following studies: Human data The Long Life Family Study (LLFS) The Long Life Family Study (LLFS) is an international collaborative study of the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited through elderly probands (generally in their 90s) who self-reported on … Data Release 24.9 | September 2024
About the Seminar SeriesThe Resilience-AD and Longevity Seminar Series aims to promote collaboration across the Alzheimer’s Disease (AD) and Exceptional Longevity (EL) research fields with the goals of highlighting research on the shared etiologies of AD risk, cognitive resilience, and EL and identifying new opportunities to cross-link AD and EL data. The seminar series is … Resilience-AD and Longevity Seminar Series
The 24.3 Data Release includes data from the following studies: Human data The Single cell transcriptomic analysis of PBMCs in Extreme Longevity (ELPSCRNA) This study provides data from 7 centenarian samples (> 100 years) and 2 younger control samples (20-59 years) from New England Centenarian Study (NECS) at Boston University and the Integrative Longevity Omics … Data Release 24.3 | March 2024
The 24.2 Data Release includes data from the following studies: Human data The AD cerebral organoid single-cell transcriptome study This study reflects supplementary research to the research pursued through the NIA-funded Longevity Genomics project (grant number U24AG051129). The study investigated the cell type-specific mechanisms involved in Alzheimer’s disease (AD) through the development of 3D cerebral … Data Release 24.2 | February 2024