Presented on May 16, 2025 by Dr. Michael Province, PhD Description: Pedigree OMIC data, such as from the Long Life Family Study (LLFS) are powerful for detecting genomic signals for aging traits, diseases and longevity. But unlike population data of unrelated individuals, pedigree data violate the basic statistical assumptions of almost all hypothesis tests and … Analysis of Pedigree OMIC Data Webinar
Welcome to the Exceptional Longevity Translational Resources (ELITE) Portal! The ELITE Portal (eliteportal.synapse.org) is a new research hub for disseminating data and other resources from translational longevity research projects. How do I use the ELITE Portal? Join us for our upcoming ELITE Portal Technical Workshop to learn how to navigate the portal, explore metadata, and … Welcome to the ELITE Portal!
The 25.2 Data Release includes data from the following studies: Human data The Long Life Family Study (LLFS), RNA Sequencing data The Long Life Family Study (LLFS) is an international collaborative effort investigating the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited based on clustering of exceptional survival, identified … Data Release 25.2 | February 2025
The 24.12 Data Release includes data from the following studies: Human data The Long Life Family Study (LLFS), Whole Genome Sequencing data The Long Life Family Study (LLFS) is an international collaborative effort investigating the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited based on clustering of exceptional survival, … Data Release 24.12 | December 2024
The 24.9 Data Release includes data from the following studies: Human data The Long Life Family Study (LLFS) The Long Life Family Study (LLFS) is an international collaborative study of the genetics and familial components of exceptional survival, longevity, and healthy aging. Families were recruited through elderly probands (generally in their 90s) who self-reported on … Data Release 24.9 | September 2024
About the Seminar SeriesThe Resilience-AD and Longevity Seminar Series aims to promote collaboration across the Alzheimer’s Disease (AD) and Exceptional Longevity (EL) research fields with the goals of highlighting research on the shared etiologies of AD risk, cognitive resilience, and EL and identifying new opportunities to cross-link AD and EL data. The seminar series is … Resilience-AD and Longevity Seminar Series
The 24.3 Data Release includes data from the following studies: Human data The Single cell transcriptomic analysis of PBMCs in Extreme Longevity (ELPSCRNA) This study provides data from 7 centenarian samples (> 100 years) and 2 younger control samples (20-59 years) from New England Centenarian Study (NECS) at Boston University and the Integrative Longevity Omics … Data Release 24.3 | March 2024
The 24.2 Data Release includes data from the following studies: Human data The AD cerebral organoid single-cell transcriptome study This study reflects supplementary research to the research pursued through the NIA-funded Longevity Genomics project (grant number U24AG051129). The study investigated the cell type-specific mechanisms involved in Alzheimer’s disease (AD) through the development of 3D cerebral … Data Release 24.2 | February 2024
The second Resilience-AD and Longevity workshop was held on November 29, 2023. It convened postdocs, principal investigators, and staff scientists involved in exceptional longevity and/or cognitive resilience research to explore opportunities for joint application of EL and AD datasets. The objectives of the workshop were to: View the recording and corresponding slides. About the EL … Resilience-AD and Longevity Workshop: Part II
The 23.8 Data Release includes data from the following studies: Human data The Characterization of gene associations with aging-related traits with a genetically-predicted transcriptome-wide association study (ADAMTS7) This study provides analyses of candidate genes and the association of Longevity-Associated Variants (LAVs) with aging-related traits and diseases. The Phenome-wide association study of aging: data files and … Data Release 23.8 | August 2023
The Exceptional Longevity Data Management and Coordination Center (EL DMCC) hosted the first Resilience-AD and Longevity workshop on June 28, 2023. The workshop brought together longevity and cognitive resilience researchers to to highlight opportunities and challenges in the field, and identify ways to leverage ELITE Portal and AD Knowledge Portal data together. View the recording … Resilience-AD and Longevity Workshop: Part I