The second Resilience-AD and Longevity workshop was held on November 29, 2023. It convened postdocs, principal investigators, and staff scientists involved in exceptional longevity and/or cognitive resilience research to explore opportunities for joint application of EL and AD datasets. The objectives of the workshop were to:
- Highlight successes, challenges, and opportunities related to crosslinking EL and AD datasets.
- Identify factors that are needed to accelerate progress in the cognitive resilience research.
- Identify research priorities and questions that cannot be answered in isolation (ie. by EL or AD alone).
- Bridge the gap between AD and EL communities by creating momentum for collaborative research opportunities.
View the recording and corresponding slides.
Workshop Agenda (click to expand)
0:00 – 5:00 | Welcoming Remarks
Presenters: Tanveer Talukdar, PhD (Sage Bionetworks) and Anna Greenwood, PhD (Sage Bionetworks)
5:00 – 23:10 | Human Longevity and Cognitive Aging: Genetic Insights from the Einstein Longevity Cohorts
Presenter: Zhengdong Zhang, PhD (Albert Einstein College of Medicine)
Moderator: Noa Rappaport, PhD (Institute for Systems Biology)
23:10 – 48:17 | Uncovering the Molecular Mechanisms of Exceptional Longevity through iPSC-based Modeling of Resiliency
Presenter: George Murphy, PhD (Boston University)
Moderator: Sofiya Milman, MD (Albert Einstein College of Medicine)
48:17 – 1:25:00 | Panel Q&A
Moderator: Catherine Kaczorowski, PhD (University of Michigan)
Panelists: George Murphy, PhD and Zhengdong Zheng, PhD
1:25:00 – 1:27:20 | Closing Remarks
Presenter: Anna Greenwood, PhD
About the EL DMCC
The mission of the Exceptional Longevity Data Management and Coordination Center (EL DMCC) is to develop and apply team-based research practices to enable exceptional longevity researchers to extend and integrate research on protective factors that contribute to exceptional health and life span.
The EL DMCC is funded by the National Institute on Aging (NIA) and is responsible for maintaining the Exceptional Longevity Translational Resources Portal (ELITE Portal), a new repository for multi-omic data on exceptionally long-lived individuals and data generated from comparative model systems. The ELITE Portal builds on infrastructure developed through the AD Knowledge Portal and launched to the NIA-funded exceptional longevity research consortia in August 2023. The portal is expected to be publicized to the public research community in 2024.