The 26.01 Data Release includes data from the following studies:

Human data

Arivale Scientific Wellness Study (SWS)

The study provides data from over 900 participants in the Arivale-Providence Feasibility Study of Scientific Wellness, a 3-year longitudinal pilot examining the impact of personalized health interventions. Data collection included clinical and functional lab tests, genetics, gut microbiome sequencing, and lifestyle and behavioral assessments combined with tailored coaching recommendations.

• This release includes a large set of Whole Genome Sequencing data, including 1,876 bam, 1,876 vcf, and 1,876 g.vcf files.
• This release also includes clinical, phenotype, wearable, metabolomic, and proteomic datasets.

Shotgun Metagenomics Analysis of the Gut Microbiome in ILO (ILOMGS)

The study provides data from 220 samples including 78 centenarian samples (over 100 years of age) and 148 younger samples (50-99). The samples were collected as part of the Integrative Longevity Omics (ILO) study. DNA extraction and shotgun metagenomics sequencing were performed on the samples for taxonomic profiling. Data consists of shotgun metagenomics sequencing data from the 220 samples.

• This release includes an updated version of the Individual, Biospecimen, and Assay metadata that includes exact ages of participants.

ILO Blood Transcriptomics (Batch 1)

This study release includes transcriptomics data of 399 blood samples from participants enrolled in the Integrative Longevity Omics project – Identifying protective omics profiles in centenarians and translating these into preventive and therapeutic strategies.

• This release includes an updated version of the Individual, Biospecimen, and Assay metadata that includes exact ages of participants.