The 25.7 Data Release includes data from the following studies:
Human data
Human Serum Determinants of Aging
This study features an investigation of human longevity using metabolomics and proteomics, data collected through a case-cohort design. Longevity cases were defined as individuals who lived longer than 98% of their peers, based on U.S. life expectancy data. Participants came from four long-term studies of older adults—MrOS, SOF, Health ABC, and CHS. A random sample of participants was selected for comparison, including some who also reached exceptional ages. Data from the CHS study are hosted on dbGaP. Data from the MrOS, SOF, and Health ABC cohorts are hosted on the ELITE Portal.
- This release provides proteomics data generated as part of the NIH-funded Longevity Consortium study, including mass spectrometry-based serum proteomics and survival data from over 3,300 participants across three large aging cohorts (Health ABC, MrOS, and SOF). Designed to identify proteins associated with exceptional longevity, the study used a case-cohort design and includes normalized peptide-level data, survival outcomes, and harmonized phenotypic covariates..
- Health ABC and additional Centenarian cohort data will be available in future data releases.